Utrecht researchers launch register for animal studies

Wednesday 24 January 2018

To improve quality of biomedical animal research, cardiovascular researchers launched a register of protocols for preclinical animal studies. The register forms part of a response to the controversy and confusion surrounding cardiac regenerative therapy. Utrecht researchers believe there is insufficient rigor in the conduct of preclinical studies. The register is announced in the journal Circulation Research.

The website www.preclinicaltrials.eu is an online register of protocols for preclinical animal studies conducted around the world. Registration of animal studies is essential in the optimization of preclinical research. With this register a reduction in the risks of reporting biases in animal studies is aimed. It will constitute a tool to avoid unnecessary duplication, improve the quality and increase transparency and sharing of knowledge in preclinical animal trials. The register is open to all, and free to use.

The initiative is supported by the ESC Working Group on Cardiovascular Regenerative and Reparative Medicine and the Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes; https://www.tacticsalliance.org/). TACTICS has recently addressed key priorities in the field of cell-based therapy for cardiac repair, identifying the efficacy of translational research as one of the main challenges to ultimately improve the quality of life of patients with ischemic disease.

The launch of the register coincides with a report from the Dutch academy of sciences “Replication studies – Improving reproducibility in the empirical sciences”. Preregistration is one of the proposed solutions in the face of the “reproducibility crisis”.

« back to the overview

No Comments